지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.2
- 수록면
- 41 - 48 (8page)
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초록· 키워드
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To enhance cyclo-His-Pro (CHP) content, soybean hydrolysate was obtained using the strains isolated from Chungkukjang and further purified by various purification steps. First, twenty two strains were screened from Chungkukjang containing high level of CHP. Among them, the strain No. 12, which showed higher productivity of CHP from soybean ferment and have homologous sequence with 16S rDNA of Bacillus amyloliquefaciens, was named B. amyloliquefaciens CHP-12. Through various purification processes, CHP was concentrated from soybean ferment using ultrafiltration, which showed the best efficiency of CHP production, with the yield (71.3%) and CHP content (2.14 mg/g). Moreover, when glucose tolerance test was performed in Type I Sprague-Dawley rat induced by streptozotocin using the soybean ferments [0.5 g soybean ferment/kg body weight (CHP-0.5 group)] and 1.0 g soybean ferment/kg body weight (CHP-1.0 group), there were significant differences in glucose levels between diabetes-control group (265.3 mg/dL) and soybean ferment-treated groups (CHP-0.5 group: 84.3 mg/dL and CHP-1.0 group: 85.3 mg/dL) 120 min after glucose injection (2 g/kg body weight) (p < 0.05). Accordingly, it is suggested that the soybean ferment containing high level of CHP might be a candidate material as an anti-diabetic supplement for manufacturing functional healthy foods.
목차
Abstract
1. 서론
2. 재료 및 방법
3. 결과 및 고찰
4. 결론
References
참고문헌 (37)
참고문헌 신청
Wang, Y / 2007 / The obesity epidemic in the United States-gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis / Epidemiol Rev 29:6~28
Porrini, E / 2010 / syndrome, insulin resistance, and chronic allograft dysfunction / Kidney Int 78:42~46
Bacha, F / 2010 / From pre-diabetes to type 2 diabetes in obese youth: pathophysiological characteristics along the spectrum of glucose dysregulation / Diabetes Care 33:2225~2231
Nanda, N / 2009 / Myocardial infarction in nondiabetic and prediabetic population: a retrospective analysis / Indian J. Physiol. Pharmacol 53:334~340
Risérus,U / 2010 / Right diet can prevent cardiometabolic diseases / Lakartidningen 107:2077~2082
Porrini, E / 2010 / syndrome, insulin resistance, and chronic allograft dysfunction / Kidney Int 78:42~46
Bacha, F / 2010 / From pre-diabetes to type 2 diabetes in obese youth: pathophysiological characteristics along the spectrum of glucose dysregulation / Diabetes Care 33:2225~2231
Nanda, N / 2009 / Myocardial infarction in nondiabetic and prediabetic population: a retrospective analysis / Indian J. Physiol. Pharmacol 53:334~340
Risérus,U / 2010 / Right diet can prevent cardiometabolic diseases / Lakartidningen 107:2077~2082
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UCI(KEPA) : I410-ECN-0101-2014-400-002396286