지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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In this study, we investigated whether the mixtures of onion water extract and aloe ethanol extracts have antiplatelet activities. The mixtures inhibited collagen- and thrombin-induced rat platelet aggregation in vitro. Additionally, the oral administration of the mixtures inhibited platelet aggregation induced by collagen ex vivo but not prolonged mouse tail vein bleeding time in vivo. These results suggest that the combination of onion and aloe extracts has a potential to be a preventive agent against platelet-mediated disorders.
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참고문헌 (21)
참고문헌 신청
Kuijpers, M. J. / 2014 / Factor XII regulates the pathological process of thrombus formation on ruptured plaques / Arterioscler. Thromb. Vasc. Biol 34:1674
Park, S. / 2009 / Methanolic extract of onion (Allium cepa) attenuates ischemia/hypoxia-induced apoptosis in cardiomyocytes via antioxidant effect / EUROPEAN JOURNAL OF NUTRITION 48:235~242
Hyun, S. W. / 2013 / Onion (Allium cepa) extract attenuates brain edema / NUTRITION 29:244~249
Singhal, A. / 2011 / Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability / Pharmacognosy Res 3:35
El-Shemy, H. A. / 2010 / Antitumor properties and modulation of antioxidant enzymes' activity by Aloe vera leaf active principles isolated via supercritical carbon dioxide extraction / Curr. Med. Chem 17:129
Park, S. / 2009 / Methanolic extract of onion (Allium cepa) attenuates ischemia/hypoxia-induced apoptosis in cardiomyocytes via antioxidant effect / EUROPEAN JOURNAL OF NUTRITION 48:235~242
Hyun, S. W. / 2013 / Onion (Allium cepa) extract attenuates brain edema / NUTRITION 29:244~249
Singhal, A. / 2011 / Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability / Pharmacognosy Res 3:35
El-Shemy, H. A. / 2010 / Antitumor properties and modulation of antioxidant enzymes' activity by Aloe vera leaf active principles isolated via supercritical carbon dioxide extraction / Curr. Med. Chem 17:129
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