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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 356 - 362 (7page)
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초록· 키워드
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An increasing number of studies have revealed an interaction between gut microbiota and tumors. The enrichment of specific bacteria strains in the intestines has been found to modulate tumor growth and influence the mechanisms of tumor treatment. Various bacteria are involved in modulating the effects of chemotherapeutic drugs currently used to treat patients with cancer, and they affect not only gastrointestinal tract tumors but also distant organ tumors. In addition, changes in the gut microbiota are known to be involved in the antitumor immune response as well as the modulation of the intestinal immune system. As a result, the gut microbiota plays an important role in modulating the efficacy of immune checkpoint inhibitors. Therefore, gut microbiota could be considered as an adjuvant treatment option with other cancer treatment or as another marker for predicting treatment response. In this review, we examine how gut microbiota affects cancer treatments.
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참고문헌 (65)
참고문헌 신청
Alexander, J. L. / 2017 / Gut microbiota modulation of chemotherapy efficacy and toxicity / Nat. Rev. Gastroenterol. Hepatol 14:356~365
Baruch, E. N. / 2021 / Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients / Science 371:602~609
Juwhan Choi / 2020 / Clinical Characteristics and Treatment of Immune-Related Adverse Events of Immune Checkpoint Inhibitors / Immune Network 20(1):1~21
Coleman, R. L. / 2013 / Latest research and treatment of advanced-stage epithelial ovarian cancer / Nat. Rev. Clin. Oncol 10:211~224
Daillere, R. / 2016 / Enterococcus hirae and Barnesiella intestinihominis facilitate cyclophosphamide-induced therapeutic immunomodulatory effects / Immunity 45:931~943
Baruch, E. N. / 2021 / Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients / Science 371:602~609
Juwhan Choi / 2020 / Clinical Characteristics and Treatment of Immune-Related Adverse Events of Immune Checkpoint Inhibitors / Immune Network 20(1):1~21
Coleman, R. L. / 2013 / Latest research and treatment of advanced-stage epithelial ovarian cancer / Nat. Rev. Clin. Oncol 10:211~224
Daillere, R. / 2016 / Enterococcus hirae and Barnesiella intestinihominis facilitate cyclophosphamide-induced therapeutic immunomodulatory effects / Immunity 45:931~943
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