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자료유형
학술저널
저자정보
Ahmed Aqsa (School of Biotechnology Jiangnan University Wuxi 214122 P.R.ChinaNational Engineering Laboratory fo) Ahmad Abdullah (Department of Industrial Biotechnology Atta-Ur-Rahman School of Applied Biosciences National Univer) Li Renhan (School of Biotechnology Jiangnan University Wuxi 214122 P.R.ChinaNational Engineering Laboratory fo) AL-Ansi Waleed (School of Food Science and Technology State Key Laboratory of Food Science and Technology Jiangnan) Fatima Momal (Department of Industrial Biotechnology National Institute of Biotechnology and Genetic Engineering) Mushtaq Bilal Sajid (School of Food Science and Technology State Key Laboratory of Food Science and Technology Jiangnan) Basharat Samra (School of Biotechnology Jiangnan University Wuxi 214122 P.R.China) Li Ye (School of Biotechnology Jiangnan University Wuxi 214122 P.R.ChinaNational Engineering Laboratory fo) Bai Zhonghu (School of Biotechnology Jiangnan University Wuxi 214122 P.R.ChinaNational Engineering Laboratory fo)
저널정보
한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제31권 제11호
발행연도
2021.11
수록면
1,465 - 1,480 (16page)
DOI
10.4014/jmb.2107.07045

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Violacein, a purple pigment first isolated from a gram-negative coccobacillus Chromobacterium violaceum, has gained extensive research interest in recent years due to its huge potential in the pharmaceutic area and industry. In this review, we summarize the latest research advances concerning this pigment, which include (1) fundamental studies of its biosynthetic pathway, (2) production of violacein by native producers, apart from C. violaceum, (3) metabolic engineering for improved production in heterologous hosts such as Escherichia coli, Citrobacter freundii, Corynebacterium glutamicum, and Yarrowia lipolytica, (4) biological/pharmaceutical and industrial properties, (5) and applications in synthetic biology. Due to the intrinsic properties of violacein and the intermediates during its biosynthesis, the prospective research has huge potential to move this pigment into real clinical and industrial applications.

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