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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 94 - 101 (8page)
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초록· 키워드
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tRNA-derived RNA fragments (tRFs) are an emerging class of non-coding RNAs (ncRNAs). A growing number of reports have shown that tRFs are not random degradation products but are functional ncRNAs made of specific tRNA cleavage. They play regulatory roles in several biological contexts such as cancer, innate immunity, stress responses, and neurological disorders. In this review, we summarize the biogenesis and functions of tRFs.
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참고문헌 (73)
참고문헌 신청
Alexander RP. / 2010 / Annotating non-coding regions of the genome / Nat Rev Genet 11:559~571
Ponting CP / 2008 / The functional repertoires of metazoan genomes / Nat Rev Genet 9:689~698
Lee YS. / 2009 / A novel class of small RNAs : tRNA-derived RNA fragments(tRFs) / Genes Dev 23:2639~2649
Emara MM. / 2010 / Angiogenin-induced tRNA-derived stressinduced RNAs promote stress-induced stress granule assembly / J Biol Chem 285:10959~10968
Wang Q. / 2013 / Identification and functional characterization of tRNA-derived RNA fragments(tRFs)in respiratory syncytial virus infection / Mol Ther 21:368~379
Ponting CP / 2008 / The functional repertoires of metazoan genomes / Nat Rev Genet 9:689~698
Lee YS. / 2009 / A novel class of small RNAs : tRNA-derived RNA fragments(tRFs) / Genes Dev 23:2639~2649
Emara MM. / 2010 / Angiogenin-induced tRNA-derived stressinduced RNAs promote stress-induced stress granule assembly / J Biol Chem 285:10959~10968
Wang Q. / 2013 / Identification and functional characterization of tRNA-derived RNA fragments(tRFs)in respiratory syncytial virus infection / Mol Ther 21:368~379
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