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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 54 - 54 (1page)
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이 논문의 연구 히스토리 (3)
2021
Determination of the metabolic alterations of short-chain fatty acids and TCA cycle intermediates in human plasma with gastric disorders using GC-MS/MS
Wonwoong Lee
,
You Lee Kim
,
Jongki Hong
한국분석과학회 학술대회
2021.11
학술대회자료
Profiling of steroid hormones in human plasma by MAD-GC-MS/MS for diagnosis of gastric disorders
Wonwoong Lee
,
Bong Chul Chung
,
Jongki Hong
한국분석과학회 학술대회
2021.05
학술대회자료
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Short-chain fatty acids (SCFAs) are produced by bacterial fermentation from dietary fiber, permeate through the intestinal cell membrane, and are distributed in the human body via blood circulation. Since absorbed SCFAs, such as acetic acid, propionic acid, and butyric acid, could introduce into tricarboxylic acid cycle (TCA cycle) in the host cells, the relationships between SCFAs and TCA cycle intermediates might influence to energy metabolism, homeostasis, and numerous disease conditions in the human body. For this reason, the information on profile changes between SCFAs and TCA cycle intermediates is required to unveil pathological mechanisms of intractable diseases including cancers. However, due to different characteristics between mono-carboxylate structured SCFAs and di-/tri- carboxylate structured TCA cycle intermediates, it demands a sophisticated analytical method. Generally, a base pairing method would be effective to decrease loss of volatile SCFAs, wh^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10819348');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
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