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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제26권 제5호
- 발행연도
- 2016.1
- 수록면
- 975 - 987 (13page)
이용수
초록· 키워드
오류제보하기
Lactobacillus plantarum (L. plantarum) is a representative probiotic. In particular, L. plantarum is the first commensal bacterium to colonize the intestine of infants. For this reason, the initial settlement of L. plantarum can play an important role in determining an infant’s health as well as their eventual health status as an adult. In addition, L. plantarum combats pathogenic infections (such as Escherichia coli (E. coli), one of the early pathogenic colonizers in an unhealthy infant gut) by secreting antimicrobial substances. The aim of this research was to determine how L. plantarum combats E. coli infection and why it is a representative probiotic in the intestine. Consequently, this research observed that E. coli releases uracil. L. plantarum specifically recognizes E. coli-derived uracil, which increases the growth rate and production of antimicrobial substance of L. plantarum. In addition, through the inhibitory activity test, this study postulates that the antimicrobial substance is a protein and can be considered a bacteriocin-like substance. Therefore, this research assumes that L. plantarum exerts its antibacterial ability by recognizing E. coli and increasing its growth rate as a result, and this phenomenon could be one of the reasons for L. plantarum settling in the intestine of infants as a beneficial bacterium.
목차
등록된 정보가 없습니다.
참고문헌 (69)
참고문헌 신청
Atrih A / 1993 / Detection of bacteriocins produced by Lactobacillus plantarum strains isolated from different foods / Microbios 75:117~123
Baba T / 2006 / Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection / Mol. Systems Biol 2:2006~2008
Bedford Russell AR / 2006 / Could peripartum antibiotics have delayed health consequences for the infant / BJOG 113:758~765
Benor S / 2014 / Probiotic supplementation in mothers of very low birth weight infants / Am. J. Perinatol 31:497~504
Biasucci G / 2010 / Mode of delivery affects the bacterial community in the newborn gut / Early Hum. Dev 86(Suppl. 1):13~15
Baba T / 2006 / Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection / Mol. Systems Biol 2:2006~2008
Bedford Russell AR / 2006 / Could peripartum antibiotics have delayed health consequences for the infant / BJOG 113:758~765
Benor S / 2014 / Probiotic supplementation in mothers of very low birth weight infants / Am. J. Perinatol 31:497~504
Biasucci G / 2010 / Mode of delivery affects the bacterial community in the newborn gut / Early Hum. Dev 86(Suppl. 1):13~15
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